Knee Osteoarthritis
Is a common condition where the cartilage that cushions your knee wears down over time. Older people and people with obesity are more at risk of developing this condition.
Common symptoms:
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Knee pain that worsens with activity and improves with rest
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Morning or after-rest stiffness (usually under 30 minutes)
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Grinding or crackling sounds with movement
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Reduced flexibility or movement
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According to the AAOS every pound of body weight places four to six pounds of pressure on each knee joint.
Study purpose
There are two different studies:
1) For people with overweight/obesity that is intended to reduce knee pain by reducing the weight
2) For people with knee osteoarthritis that failed conservative treatment, this one will compare removing the lose cartilage from your knee alone vs. with the addition of stem cells, this is intended to regenerate your cartilage.
Requirements
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18 years of age or older
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Having pain in the knee, morning stiffness, a crackling sound on your knee.​
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Overall healthy or with chronic conditions controlled
Major Disqualifications​
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Currently pregnant or breastfeeding
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Substance abuse
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Recent knee injections or steroids use
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Uncontrolled chronic conditions
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Contraindications for imagining studies
Schedule:
Study 1: visits every 4-6 weeks
Study 2: 2 weeks follow-up visit after procedure, then visits every 3 months during the first year, then every 6 months
Duration
Study 1: Around 75 weeks
Study 2: Around 27 months
Both include screening period, treatment and follow up period.
Northwest Clinic - Gonzaba Medical Group
7219 Culebra Rd
San Antonio, TX 78251
Research Line: 210-756-6802